FAP: BMP

Pathway ID: SIGNOR-FapBMP

Description: Bone morphogenetic proteins (BMPs),bind to two different serine/threonine kinase receptors (type I and type II receptors), and propagate their signals through Smad-dependent and Smad-independent pathways. BMPs cause several different cellular effects, such as stem cell maintenance, migration, differentiation, proliferation and apoptosis. A ligand might induce different effects depending on the cellular context.

complexity level

level 1 seed interactions
level 2 connect
level 3 first neighbors
level 4 all
level 5 PPI

28 Seed Entities

Organism:
Name Primary ID
ALPL P05186
AXIN1 O15169
BMP2 P12643
BMPR1A P36894
BMPR2 Q13873
DLX3 O60479
DLX5 P56178
GDF6 Q6KF10
HOXC8 P31273
MAP2K3 P46734
MAP3K7 O43318
MAPK14 Q16539
NOG Q13253
Osteoblast Differentiation SIGNOR-PH9
RUNX2 Q13950
SHH Q15465
SMAD1 Q15797
SMAD2 Q15796
SMAD3 P84022
SMAD4 Q13485
SMAD5 Q99717
SMAD6 O43541
SMAD7 O15105
SMURF1 Q9HCE7
STUB1 Q9UNE7
TGFB1 P01137
TGFBR1 P36897
TRAF6 Q9Y4K3