Satellite: Calcium&myogenesis

Pathway ID: SIGNOR-ScCA

Description: IGF1 is an important regulator of muscle growth in vivo. IGF1 activates signaling pathways that influence muscle response. IGF1 increases calcium influx, thereby promoting the activation of calcineurin, which in turn activates transcription factors, such as MEF2 and MYOD, leading to muscle differentiation.

Curated by: Alessandro Palma

12 Seed Entities

Organism:
Name Primary ID
CALM1 P0DP23
IGF1R P08069
NFATC1 O95644
MYOD1 P15172
IGF1 P05019
cyclosporin A CHEBI:4031
calcium(2+) CHEBI:29108
Skeletal_muscle_differentiation SIGNOR-PH1
MEF2C Q06413
Myotube_hypertrophy SIGNOR-PH20
Calcineurin SIGNOR-C155
MYOG P15173