Summary

Name MSI1
Full Name RNA-binding protein Musashi homolog 1
Synonyms Musashi-1
Primary ID O43347
Links - -
Type protein
Relations 3
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ CCND1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MSI1 0.29
Publications: 1 Organism: Homo Sapiens
+ ERBB2up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MSI1 0.271
Publications: 1 Organism: Homo Sapiens
+ MSI1down-regulates img/direct_inhibition.png binding NUMB 0.464
Publications: 1 Organism: Homo Sapiens