Summary

Name ZBTB14
Full Name Zinc finger and BTB domain-containing protein 14
Synonyms Zinc finger protein 161 homolog, Zfp-161, Zinc finger protein 478, Zinc finger protein 5 homolog, ZF5, Zfp-5, hZF5 | ZFP161, ZNF478
Primary ID O43829
Links - -
Type protein
Relations 3
Function Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation MYC 0.324
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png binding ZBTB14 0.291
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png binding ZBTB14 0.2
Publications: 1 Organism: Homo Sapiens