Summary

Name KALRN
Full Name Kalirin
Synonyms Huntingtin-associated protein-interacting protein, Protein Duo, Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain | DUET, DUO, HAPIP, TRAD
Primary ID O60229
Links - -
Type protein
Relations 2
Function Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation KALRN 0.352
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png phosphorylation KALRN 0.375
Publications: 1 Organism: In Vitro