Summary

Name DOK2
Full Name Docking protein 2
Synonyms Downstream of tyrosine kinase 2, p56(dok-2) |
Primary ID O60496
Links - -
Type protein
Relations 1
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png dephosphorylation DOK2 0.2
Publications: 1 Organism: In Vitro