Summary

Name GABARAP
Full Name Gamma-aminobutyric acid receptor-associated protein
Synonyms GABA(A) receptor-associated protein, MM46 | FLC3B
Primary ID O95166
Links - -
Type protein
Relations 8
Pathways Autophagy
Function Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding GABARAP 0.90
Publications: 1 Organism: In Vitro
Pathways:Autophagy
+ up-regulates activity img/direct-activation.png cleavage GABARAP 0.95
Publications: 1 Organism: In Vitro
Pathways:Autophagy
+ up-regulates activity img/direct-activation.png binding mTORC1
Publications: 1 Organism: Homo Sapiens
Tissue: HeLa Cell
Pathways:Autophagy
+ up-regulates img/direct-activation.png binding GABARAP 0.66
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates img/direct-activation.png binding GABARAP 0.75
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GABARAP
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding TBC1D25 0.42
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GABARAP 0.53
Publications: 1 Organism: Homo Sapiens