| + |
TLE1 | up-regulates activity 
binding
|
SIX6 |
0.406 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-234592 |
|
|
in vitro |
|
| pmid |
sentence |
| 12441302 |
Biochemical and mutational analysis shows that the Six domain of both SIX3 and SIX6 strongly interact with the QD domain of TLE1 and AES. TLE1 over-expression induces an enlargement of the eye field and reinforcesSIX3/SIX6 capability of initiating retina formation |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
TLE5 | down-regulates activity 
binding
|
SIX6 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-234589 |
|
|
in vitro |
|
| pmid |
sentence |
| 12441302 |
Biochemical and mutational analysis shows that the Six domain of both SIX3 and SIX6 strongly interact with the QD domain of TLE1 and AES. AES abrogates SIX3- and SIX6-induced phenotypes |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
SIX6
- 
- 