Summary

Name IGFBP1
Full Name Insulin-like growth factor-binding protein 1
Synonyms IBP-1, IGF-binding protein 1, IGFBP-1, Placental protein 12, PP12 | IBP1
Primary ID P08833
Links - -
Type protein
Relations 4
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.

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Relations

Regulator Mechanism target score ℹ
+ HOXA10down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation IGFBP1 0.426
Publications: 1 Organism: Homo Sapiens
+ HOXB4up-regulates quantity by expression img/direct-activation.png transcriptional regulation IGFBP1 0.2
Publications: 1 Organism: Homo Sapiens
+ FOXOup-regulates quantity by expression img/indirect-activation.png transcriptional regulation IGFBP1 0.2
Publications: 1 Organism: Homo Sapiens
+ FOXO1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation IGFBP1 0.392
Publications: 1 Organism: Homo Sapiens