Summary

Name CYP2C9
Full Name Cytochrome P450 2C9
Synonyms (R)-limonene 6-monooxygenase, 1.14.13.80, (S)-limonene 6-monooxygenase, 1.14.13.48, (S)-limonene 7-monooxygenase, 1.14.13.49, CYPIIC9, Cholesterol 25-hydroxylase, 1.14.99.38, Cytochrome P-450MP, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 PB-1, S-mephenytoin 4-hydroxylase | CYP2C10
Primary ID P11712
Links - -
Type protein
Relations 2
Inhibitors baicalein; apigenin
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (PubMed:25994031). This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan (PubMed:25994031).

Viewer

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png chemical inhibition CYP2C9
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition CYP2C9
Publications: 1 Organism: Homo Sapiens