Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-256507 |
Tyr141 |
STVLTSKyR |
in vitro |
|
pmid |
sentence |
8635221 |
Both human plasma carboxypeptidase N (CPN) and membrane-bound carboxypeptidase M (CPM) released the C-terminal arginine (alpha-Arg141) of the alpha chain of human adult hemoglobin. Thus, the hydrolysis of hemoglobin by CPM and CPN demonstrated the contribution of the alpha-Arg141 residue to sustaining the tetrameric structure of hemoglobin and its normal oxygen affinity and vasoactivity. |
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