Summary

Name DDX6
Full Name Probable ATP-dependent RNA helicase DDX6
Synonyms ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK | HLR2, RCK
Primary ID P26196
Links - -
Type protein
Relations 2
Function Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions (PubMed:25995375, PubMed:27342281, PubMed:31422817). Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation (PubMed:27342281). In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts (PubMed:26098573).

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Relations

Regulator Mechanism target score
+ img/unknown.png binding DDX6 0.56
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png binding DDX6 0.592
Publications: 1 Organism: Homo Sapiens