Summary

Name GJB2
Full Name Gap junction beta-2 protein
Synonyms Connexin-26, Cx26
Primary ID P29033
Links - -
Type protein
Relations 1
Function Structural component of gap junctions (PubMed:17551008, PubMed:19340074, PubMed:21094651, PubMed:26753910, PubMed:16849369, PubMed:19384972). Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (PubMed:17551008, PubMed:19340074, PubMed:21094651, PubMed:26753910). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (PubMed:21094651, PubMed:16849369, PubMed:19384972).

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Relations

Regulator Mechanism target score ℹ
+ DNM2down-regulates img/direct_inhibition.png binding GJB2 0.339
Publications: 1 Organism: Homo Sapiens