Summary

Name SERPINF1
Full Name Pigment epithelium-derived factor
Synonyms PEDF, Cell proliferation-inducing gene 35 protein, EPC-1, Serpin F1 | PEDF
Primary ID P36955
Links - -
Type protein
Relations 2
Function Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Viewer

Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation SERPINF1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation SERPINF1 0.315
Publications: 1 Organism: Homo Sapiens