Summary

Name MC3R
Full Name Melanocortin receptor 3
Synonyms MC3-R
Primary ID P41968
Links - -
Type protein
Relations 7
Function Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding MC3R 0.93
Publications: 1 Organism: Homo Sapiens
Tissue: Skin
+ down-regulates activity img/direct_inhibition.png binding MC3R 0.42
Publications: 1 Organism: Cricetulus Griseus
+ down-regulates activity img/direct_inhibition.png binding MC3R 0.56
Publications: 1 Organism: Cricetulus Griseus
+ down-regulates activity img/direct_inhibition.png binding MC3R 0.93
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding MC3R
Publications: 1
Tissue: Hypothalamus
+ up-regulates activity img/direct-activation.png binding MC3R 0.27
Publications: 1
Tissue: Hypothalamus
+ up-regulates activity img/direct-activation.png unknown GNAS
Publications: 1
Tissue: Hypothalamus