Summary

Name CDKN2C
Full Name Cyclin-dependent kinase 4 inhibitor C
Synonyms Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6 | CDKN6
Primary ID P42773
Links - -
Type protein
Relations 5
Function Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ CDKN2Cdown-regulates img/direct_inhibition.png binding CDK4 0.865
Publications: 1 Organism: Homo Sapiens
+ MEN1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CDKN2C 0.506
Publications: 1 Organism: Homo Sapiens
+ KLF1up-regulates quantity by expression img/direct-activation.png transcriptional regulation CDKN2C 0.269
Publications: 1 Organism: Drosophila Melanogaster
+ CDKN2Cdown-regulates img/direct_inhibition.png binding CDK6 0.873
Publications: 1 Organism: Homo Sapiens
+ DNMT3Adown-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation CDKN2C 0.35
Publications: 1 Organism: Homo Sapiens