Summary

Name GLP1R
Full Name Glucagon-like peptide 1 receptor
Synonyms GLP-1 receptor, GLP-1-R, GLP-1R
Primary ID P43220
Links - -
Type protein
Relations 2
Function G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation GLP1R 0.344
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GLP1R 0.776
Publications: 1 Organism: Homo Sapiens