Summary

Name MKI67
Full Name Proliferation marker protein Ki-67
Synonyms Antigen identified by monoclonal antibody Ki-67, Antigen KI-67, Antigen Ki67 |
Primary ID P46013
Links - -
Type protein
Relations 1
Function Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MKI67 0.2
Publications: 1 Organism: Homo Sapiens