Summary

Name PCBD1
Full Name Pterin-4-alpha-carbinolamine dehydratase
Synonyms PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, DCoH, Dimerization cofactor of HNF1, Phenylalanine hydroxylase-stimulating protein, Pterin carbinolamine dehydratase, PCD | DCOH, PCBD
Primary ID P61457
Links - -
Type protein
Relations 2
Function Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation FXYD2 0.358
Publications: 1 Organism: Homo Sapiens
Tissue: Renal Distal Tubule
+ up-regulates activity img/direct-activation.png binding HNF1B 0.6
Publications: 1 Organism: Homo Sapiens
Tissue: Renal Distal Tubule