Summary

Name CHAF1B
Full Name Chromatin assembly factor 1 subunit B
Synonyms CAF-1 subunit B, Chromatin assembly factor I p60 subunit, CAF-I 60 kDa subunit, CAF-I p60, M-phase phosphoprotein 7 | CAF1A, CAF1P60, MPHOSPH7, MPP7
Primary ID Q13112
Links - -
Type protein
Relations 1
Function Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation MGMT 0.3
Publications: 1 Organism: Homo Sapiens