Summary

Name MTMR3
Full Name Myotubularin-related protein 3
Synonyms FYVE domain-containing dual specificity protein phosphatase 1, FYVE-DSP1, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, 3.1.3.95, Phosphatidylinositol-3-phosphate phosphatase, 3.1.3.64, Zinc finger FYVE domain-containing protein 10 | KIAA0371, ZFYVE10
Primary ID Q13615
Links - -
Type protein
Relations 4
Function Phosphatase that acts on lipids with a phosphoinositol headgroup (PubMed:11676921). Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:11676921). May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues (PubMed:10733931).

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Relations

Regulator Mechanism target score ℹ
+ MTMR3down-regulates quantity img/direct_inhibition.png chemical modification 1-phosphatidyl-1D-myo-inositol 3-phosphate(3-) 0.8
Publications: 1 Organism: Homo Sapiens
+ MTMR3up-regulates quantity img/direct-activation.png chemical modification 1-phosphatidyl-1D-myo-inositol(1-) 0.8
Publications: 1 Organism: Homo Sapiens
+ MTMR3down-regulates activity img/direct_inhibition.png mTORC1 0.313
Publications: 1 Organism: Homo Sapiens
Pathways:Autophagy
+ MTMR3down-regulates activity img/direct_inhibition.png MTOR 0.362
Publications: 1 Organism: Homo Sapiens