Summary

Name IHH
Full Name Indian hedgehog protein
Synonyms IHH, HHG-2
Primary ID Q14623
Links - -
Type protein
Relations 5
Pathways Sonic Hedgehog
Function Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding PTCH1 0.833
Publications: 1 Organism: Homo Sapiens
Tissue: Skin
Pathways:Sonic Hedgehog
+ down-regulates activity img/direct_inhibition.png binding IHH 0.701
Publications: 1 Organism: Mus Musculus
Pathways:Sonic Hedgehog
+ up-regulates img/indirect-activation.png BMP2 0.539
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding PTCH2 0.783
Publications: 1 Organism: Homo Sapiens
Tissue: Skin