Summary

Name CDK10
Full Name Cyclin-dependent kinase 10
Synonyms Cell division protein kinase 10, Serine/threonine-protein kinase PISSLRE |
Primary ID Q15131
Links - -
Type protein
Relations 2
Function Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) (PubMed:24218572). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling (PubMed:27104747).

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png phosphorylation ETS2 0.549
Publications: 2 Organism: Homo Sapiens