Summary

Name RABEP1
Full Name Rab GTPase-binding effector protein 1
Synonyms Rabaptin-4, Rabaptin-5, Rabaptin-5alpha, Renal carcinoma antigen NY-REN-17 | RAB5EP, RABPT5, RABPT5A
Primary ID Q15276
Links - -
Type protein
Relations 2
Function Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding RABGEF1 0.941
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding RAB5A 0.927
Publications: 1 Organism: Homo Sapiens