Summary

Name ESCO1
Full Name N-acetyltransferase ESCO1
Synonyms CTF7 homolog 1, Establishment factor-like protein 1, EFO1p, hEFO1, Establishment of cohesion 1 homolog 1, ECO1 homolog 1, ESO1 homolog 1 | EFO1, KIAA1911
Primary ID Q5FWF5
Links - -
Type protein
Relations 2
Function Acetyltransferase required for the establishment of sister chromatid cohesion (PubMed:15958495, PubMed:18614053). Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3 (PubMed:18614053).

Viewer

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation ESCO1 0.492
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation ESCO1 0.444
Publications: 1 Organism: Homo Sapiens