| + |
EPGN | up-regulates 
binding
|
ERBB4 |
0.409 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-144399 |
|
|
Homo sapiens |
Skeletal Muscle Cancer Cell |
| pmid |
sentence |
| 16469638 |
They both bind to betacellulin and the heparin-binding ligand, hb-egf, as well as to two low-affinity ligands, epiregulin and epigen. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-147835 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16829981 |
Areg (amphiregulin), btc (beta-cellulin), egf, epgn (epigen), ereg (epiregulin), hbegf, nrg1, nrg2, nrg3, nrg4 and tgfa (tgfalpha) constitute egf family ligands for erbb family receptors. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
EPGN | up-regulates
binding
|
EGFR |
0.641 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-165779 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20513444 |
Remarkably, three members of the epidermal growth factor (egf) family (ereg, areg, and epgn) showed increased expression that was associated with elevated epidermal activation of the egf receptor (egfr) and stat3, a downstream effector of egfr signaling. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Skin |
3.0
EPGN
- 
- 