3.0
Summary
| Name |  FGD2
|
| Full Name | FYVE, RhoGEF and PH domain-containing protein 2 |
| Synonyms | Zinc finger FYVE domain-containing protein 4 | ZFYVE4 |
| Primary ID | Q7Z6J4 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate (By similarity). |
guanine nucleotide exchange factor