Summary

Name NETO2
Full Name Neuropilin and tolloid-like protein 2
Synonyms Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2 | BTCL2
Primary ID Q8NC67
Links - -
Type protein
Relations 1
Function Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation NETO2 0.262
Publications: 1 Organism: Homo Sapiens