Summary

Name EXT2
Full Name Exostosin-2
Synonyms Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 2, Putative tumor suppressor protein EXT2
Primary ID Q93063
Links - -
Type protein
Relations 1
Function Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding EXT1/EXT2 0.558
Publications: 1 Organism: Homo Sapiens