Summary

Name ZFP91
Full Name E3 ubiquitin-protein ligase ZFP91
Synonyms Zinc finger protein 757, Zinc finger protein 91 homolog, Zfp-91 | ZNF757
Primary ID Q96JP5
Links - -
Type protein
Relations 1
Function Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png ubiquitination MAP3K14 0.519
Publications: 1 Organism: Homo Sapiens