Summary

Name NACC1
Full Name Nucleus accumbens-associated protein 1
Synonyms NAC-1, BTB/POZ domain-containing protein 14B | BTBD14B, NAC1
Primary ID Q96RE7
Links - -
Type protein
Relations 1
Function Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding ZBTB14 0.291
Publications: 1 Organism: In Vitro