Summary

Name ERBIN
Full Name Erbin
Synonyms Densin-180-like protein, Erbb2-interacting protein, Protein LAP2 | ERBB2IP, KIAA1225, LAP2
Primary ID Q96RT1
Links - -
Type protein
Relations 2
Function Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state (PubMed:16203728). Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding ERBIN 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding ERBIN 0.2
Publications: 1 Organism: Homo Sapiens