Summary

Name IL12RB2
Full Name Interleukin-12 receptor subunit beta-2
Synonyms IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2
Primary ID Q99665
Links - -
Type protein
Relations 1
Function Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding IL12RB2 0.556
Publications: 1 Organism: Homo Sapiens