Summary

Name ARHGAP9
Full Name Rho GTPase-activating protein 9
Synonyms Rho-type GTPase-activating protein 9 |
Primary ID Q9BRR9
Links - -
Type protein
Relations 1
Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png gtpase-activating protein RAC1 0.588
Publications: 1 Organism: Homo Sapiens