Summary

Name GRPEL1
Full Name GrpE protein homolog 1, mitochondrial
Synonyms HMGE, Mt-GrpE#1 | GREPEL1
Primary ID Q9HAV7
Links - -
Type protein
Relations 2
Function Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (PubMed:11311562).

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding HSPA8 0.64
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding TIM23 complex 0.594
Publications: 1