Summary

Name CRLF2
Full Name Cytokine receptor-like factor 2
Synonyms Cytokine receptor-like 2, IL-XR, Thymic stromal lymphopoietin protein receptor, TSLP receptor | CRL2, ILXR, TSLPR
Primary ID Q9HC73
Links - -
Type protein
Relations 1
Function Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding CRLF2 0.922
Publications: 1 Organism: Homo Sapiens