| + |
GATA1 | up-regulates quantity by expression 
transcriptional regulation
|
GP6 |
0.288 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254081 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12377757 |
We have determined that the GP6 sequence -191 to -39 represents the core promoter and that transcription is driven largely by GATA-1 (-176) and c-Ets-1 (-45) sites within this segment. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254158 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12359731 |
Deletion analyses and site-directed mutagenesis identified Sp1(227), GATA(177), and Ets(48) sites as essential for GPVI expression. We show that transcription factors GATA-1, Fli-1, and Sp1 can bind to and activate this promoter. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
ETS1 | up-regulates quantity by expression
transcriptional regulation
|
GP6 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254082 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12377757 |
We have determined that the GP6 sequence -191 to -39 represents the core promoter and that transcription is driven largely by GATA-1 (-176) and c-Ets-1 (-45) sites within this segment. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FLI1 | up-regulates quantity by expression
transcriptional regulation
|
GP6 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254157 |
|
|
Homo sapiens |
Megakaryocyte Cell Line |
| pmid |
sentence |
| 12359731 |
Deletion analyses and site-directed mutagenesis identified Sp1(227), GATA(177), and Ets(48) sites as essential for GPVI expression. We show that transcription factors GATA-1, Fli-1, and Sp1 can bind to and activate this promoter. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SP1 | up-regulates quantity by expression
transcriptional regulation
|
GP6 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254159 |
|
|
Homo sapiens |
Megakaryocyte Cell Line |
| pmid |
sentence |
| 12359731 |
Deletion analyses and site-directed mutagenesis identified Sp1(227), GATA(177), and Ets(48) sites as essential for GPVI expression. We show that transcription factors GATA-1, Fli-1, and Sp1 can bind to and activate this promoter. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
GP6
- 
- 