Summary

Name CD209
Full Name CD209 antigen
Synonyms C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1 | CLEC4L
Primary ID Q9NNX6
Links - -
Type protein
Relations 1
Function Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding CD209 0.2
Publications: 1 Organism: Homo Sapiens