Summary

Name MIOS
Full Name GATOR complex protein MIOS
Synonyms Missing oocyte meiosis regulator homolog |
Primary ID Q9NXC5
Links - -
Type protein
Relations 1
Function As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).

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Relations

Regulator Mechanism target score ℹ
+ MIOSform complex img/form-complex.png binding GATOR2 0.943
Publications: 1 Organism: Homo Sapiens