Entity Details

Name DENND3
ID A2RUS2
Role substrate
Enzymatic Domains
uDENN 1-163
PROSITE-ProRule
cDENN 186-318
PROSITE-ProRule
dDENN 320-424
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ULK2DENND3Ser490
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ELAPRNSsLRLTDTAphosphorylation
up-regulates activity		25925668SIGNOR-264733
ULK1DENND3Ser472
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THRRMVVsMPNLQDIphosphorylation
up-regulates activity		25925668SIGNOR-264730
ULK1DENND3Ser490
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ELAPRNSsLRLTDTAphosphorylation
up-regulates activity		25925668SIGNOR-264731
ULK2DENND3Ser472
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THRRMVVsMPNLQDIphosphorylation
up-regulates activity		25925668SIGNOR-264732
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ULK2phosphorylation
up-regulates
→
DENND3
PSer490		phosphorylation
up-regulates
→		DENND325925668SIGNOR-264733
ULK1phosphorylation
up-regulates
→
DENND3
PSer472		phosphorylation
up-regulates
→		DENND325925668SIGNOR-264730
ULK1phosphorylation
up-regulates
→
DENND3
PSer490		phosphorylation
up-regulates
→		DENND325925668SIGNOR-264731
ULK2phosphorylation
up-regulates
→
DENND3
PSer472		phosphorylation
up-regulates
→		DENND325925668SIGNOR-264732
Regulator Mechanism/Effect Target SIGNOR-ID
ULK2phosphorylation
→
up-regulates activity 		DENND3SIGNOR-264733
ULK1phosphorylation
→
up-regulates activity 		DENND3SIGNOR-264730
ULK1phosphorylation
→
up-regulates activity 		DENND3SIGNOR-264731
ULK2phosphorylation
→
up-regulates activity 		DENND3SIGNOR-264732