Entity Details

Name	MCRIP1
ID	C9JLW8
Role	substrate
Enzymatic Domains
View in

Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPK3	MCRIP1	Thr30 View in OncoXplorer	PSSSEIFtPAHEENV	phosphorylation down-regulates activity	25728771	SIGNOR-264772
MAPK1	MCRIP1	Thr30 View in OncoXplorer	PSSSEIFtPAHEENV	phosphorylation down-regulates activity	25728771	SIGNOR-264774
Gbeta	MCRIP1	–		phosphorylation down-regulates activity	25728771	SIGNOR-270092
MAPK3	MCRIP1	Ser21 View in OncoXplorer	KRTSSPRsPPSSSEI	phosphorylation down-regulates activity	25728771	SIGNOR-264773
MAPK1	MCRIP1	Ser21 View in OncoXplorer	KRTSSPRsPPSSSEI	phosphorylation down-regulates activity	25728771	SIGNOR-264775
ERK1/2	MCRIP1	–		phosphorylation down-regulates activity	25728771	SIGNOR-270188

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK3	phosphorylation up-regulates →	MCRIP1 PThr30	phosphorylation down-regulates ⊣	MCRIP1	25728771	SIGNOR-264772
MAPK1	phosphorylation up-regulates →	MCRIP1 PThr30	phosphorylation down-regulates ⊣	MCRIP1	25728771	SIGNOR-264774
MAPK3	phosphorylation up-regulates →	MCRIP1 PSer21	phosphorylation down-regulates ⊣	MCRIP1	25728771	SIGNOR-264773
MAPK1	phosphorylation up-regulates →	MCRIP1 PSer21	phosphorylation down-regulates ⊣	MCRIP1	25728771	SIGNOR-264775

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPK3	phosphorylation → down-regulates activity	MCRIP1	SIGNOR-264772
MAPK1	phosphorylation → down-regulates activity	MCRIP1	SIGNOR-264774
Gbeta	phosphorylation → down-regulates activity	MCRIP1	SIGNOR-270092
MAPK3	phosphorylation → down-regulates activity	MCRIP1	SIGNOR-264773
MAPK1	phosphorylation → down-regulates activity	MCRIP1	SIGNOR-264775
ERK1/2	phosphorylation → down-regulates activity	MCRIP1	SIGNOR-270188