| Name | KIF2A |
| ID | O00139 |
| Role | substrate |
| Enzymatic Domains |
Kinesin motor 223-553 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | KIF2A | Thr554 | ANRVKELtVDPTAAG | phosphorylation up-regulates activity | 25660017 | SIGNOR-278380 |
| TTBK2 | KIF2A | Ser135 | SSAQQNGsVSDISPV | phosphorylation down-regulates activity | 26323690 | SIGNOR-260926 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | KIF2A PThr554 | phosphorylation up-regulates → | KIF2A | 25660017 | SIGNOR-278380 |
| TTBK2 | phosphorylation up-regulates → | KIF2A PSer135 | phosphorylation down-regulates ⊣ | KIF2A | 26323690 | SIGNOR-260926 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | phosphorylation → up-regulates activity | KIF2A | SIGNOR-278380 |
| TTBK2 | phosphorylation → down-regulates activity | KIF2A | SIGNOR-260926 |