| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates | 12387817 | SIGNOR-236800 |
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates | 15209375 | SIGNOR-236637 |
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates activity | 10191262 | SIGNOR-250275 |
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates | 10191262 | SIGNOR-236796 |
| PDPK2P | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates | 10191262 | SIGNOR-66234 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 12387817 | SIGNOR-236800 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 15209375 | SIGNOR-236637 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 10191262 | SIGNOR-250275 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 10191262 | SIGNOR-236796 |
| PDPK2P | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 10191262 | SIGNOR-66234 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PDPK1 | phosphorylation → up-regulates | SGK1 | SIGNOR-236800 |
| PDPK1 | phosphorylation → up-regulates | SGK1 | SIGNOR-236637 |
| PDPK1 | phosphorylation → up-regulates activity | SGK1 | SIGNOR-250275 |
| PDPK1 | phosphorylation → up-regulates | SGK1 | SIGNOR-236796 |
| PDPK2P | phosphorylation → up-regulates | SGK1 | SIGNOR-66234 |
