| Name | BMPR1B |
| ID | O00238 |
| Role | kinase |
| Enzymatic Domains |
GS 174-203 PROSITE-ProRule
Protein kinase 204-494 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BMPR1B | SMAD9 | – | phosphorylation up-regulates | 19620713 | SIGNOR-187196 | |
| BMPR1B | SMAD9 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255264 | |
| BMPR1B | STAMBP | Ser2 | sDHGDVSL | phosphorylation up-regulates activity | 11483516 | SIGNOR-250596 |
| BMPR1B | STAMBP | Ser243 | SLKPGALsNSESIPT | phosphorylation up-regulates activity | 11483516 | SIGNOR-250597 |
| BMPR1B | STAMBP | Ser245 | KPGALSNsESIPTID | phosphorylation up-regulates activity | 11483516 | SIGNOR-250598 |
| BMPR1B | STAMBP | Ser247 | GALSNSEsIPTIDGL | phosphorylation up-regulates activity | 11483516 | SIGNOR-250599 |
| BMPR1B | STAMBP | Ser48 | VEIIRMAsIYSEEGN | phosphorylation up-regulates activity | 11483516 | SIGNOR-250600 |
| BMPR1B | SMAD1 | – | phosphorylation up-regulates | 19620713 | SIGNOR-187190 | |
| BMPR1B | SMAD1 | Ser462 | GSPHNPIsSVS | phosphorylation up-regulates | 9335504 | SIGNOR-52662 |
| BMPR1B | SMAD1 | Ser463 | SPHNPISsVS | phosphorylation up-regulates | 9335504 | SIGNOR-52666 |
| BMPR1B | SMAD1 | Ser465 | HNPISSVs | phosphorylation up-regulates | 9335504 | SIGNOR-52670 |
| BMPR1B | SMAD1 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255265 | |
| BMPR1B | SMAD5 | – | phosphorylation up-regulates | 19620713 | SIGNOR-187193 | |
| BMPR1B | SMAD5 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255260 | |
| BMPR1B | SMAD1/5/8 | – | phosphorylation up-regulates | 9335504 | SIGNOR-269846 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BMPR1B | phosphorylation up-regulates → | STAMBP PSer2 | phosphorylation up-regulates → | STAMBP | 11483516 | SIGNOR-250596 |
| BMPR1B | phosphorylation up-regulates → | STAMBP PSer243 | phosphorylation up-regulates → | STAMBP | 11483516 | SIGNOR-250597 |
| BMPR1B | phosphorylation up-regulates → | STAMBP PSer245 | phosphorylation up-regulates → | STAMBP | 11483516 | SIGNOR-250598 |
| BMPR1B | phosphorylation up-regulates → | STAMBP PSer247 | phosphorylation up-regulates → | STAMBP | 11483516 | SIGNOR-250599 |
| BMPR1B | phosphorylation up-regulates → | STAMBP PSer48 | phosphorylation up-regulates → | STAMBP | 11483516 | SIGNOR-250600 |
| BMPR1B | phosphorylation up-regulates → | SMAD1 PSer462 | phosphorylation up-regulates → | SMAD1 | 9335504 | SIGNOR-52662 |
| BMPR1B | phosphorylation up-regulates → | SMAD1 PSer463 | phosphorylation up-regulates → | SMAD1 | 9335504 | SIGNOR-52666 |
| BMPR1B | phosphorylation up-regulates → | SMAD1 PSer465 | phosphorylation up-regulates → | SMAD1 | 9335504 | SIGNOR-52670 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| BMPR1B | phosphorylation → up-regulates | SMAD9 | SIGNOR-187196 |
| BMPR1B | phosphorylation → up-regulates activity | SMAD9 | SIGNOR-255264 |
| BMPR1B | phosphorylation → up-regulates activity | STAMBP | SIGNOR-250596 |
| BMPR1B | phosphorylation → up-regulates activity | STAMBP | SIGNOR-250597 |
| BMPR1B | phosphorylation → up-regulates activity | STAMBP | SIGNOR-250598 |
| BMPR1B | phosphorylation → up-regulates activity | STAMBP | SIGNOR-250599 |
| BMPR1B | phosphorylation → up-regulates activity | STAMBP | SIGNOR-250600 |
| BMPR1B | phosphorylation → up-regulates | SMAD1 | SIGNOR-187190 |
| BMPR1B | phosphorylation → up-regulates | SMAD1 | SIGNOR-52662 |
| BMPR1B | phosphorylation → up-regulates | SMAD1 | SIGNOR-52666 |
| BMPR1B | phosphorylation → up-regulates | SMAD1 | SIGNOR-52670 |
| BMPR1B | phosphorylation → up-regulates activity | SMAD1 | SIGNOR-255265 |
| BMPR1B | phosphorylation → up-regulates | SMAD5 | SIGNOR-187193 |
| BMPR1B | phosphorylation → up-regulates activity | SMAD5 | SIGNOR-255260 |
| BMPR1B | phosphorylation → up-regulates | SMAD1/5/8 | SIGNOR-269846 |