Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CSNK1A1	CBX4	Thr437	ARSISTPtCLGGSPA	phosphorylation down-regulates quantity by destabilization	32111827	SIGNOR-277512
HIPK2	CBX4	–		phosphorylation up-regulates activity	17018294	SIGNOR-278484

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CSNK1A1	phosphorylation up-regulates →	CBX4 PThr437	phosphorylation down-regulates ⊣	CBX4	32111827	SIGNOR-277512

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CSNK1A1	phosphorylation down-regulates quantity by destabilization	CBX4	SIGNOR-277512
HIPK2	phosphorylation → up-regulates activity	CBX4	SIGNOR-278484