Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK11B	EIF3F	Ser46	PAAAPASsSDPAAAA	phosphorylation down-regulates	12446680	SIGNOR-95762
CyclinD3/CDK11B	EIF3F	Thr119	GAARVIGtLLGTVDK	phosphorylation up-regulates activity	19245811	SIGNOR-273132
CyclinD3/CDK11B	EIF3F	Ser46	PAAAPASsSDPAAAA	phosphorylation up-regulates activity	19245811	SIGNOR-273134
CDK11B	EIF3F	Thr119	GAARVIGtLLGTVDK	phosphorylation up-regulates activity	19245811	SIGNOR-273131
CDK11B	EIF3F	Thr119	GAARVIGtLLGTVDK	phosphorylation unknown	19245811	SIGNOR-184185
CDK11B	EIF3F	Ser46	PAAAPASsSDPAAAA	phosphorylation up-regulates activity	19245811	SIGNOR-273133

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK11B	phosphorylation up-regulates →	EIF3F PSer46	phosphorylation down-regulates ⊣	EIF3F	12446680	SIGNOR-95762
CyclinD3/CDK11B	phosphorylation up-regulates →	EIF3F PThr119	phosphorylation up-regulates →	EIF3F	19245811	SIGNOR-273132
CyclinD3/CDK11B	phosphorylation up-regulates →	EIF3F PSer46	phosphorylation up-regulates →	EIF3F	19245811	SIGNOR-273134
CDK11B	phosphorylation up-regulates →	EIF3F PThr119	phosphorylation up-regulates →	EIF3F	19245811	SIGNOR-273131
CDK11B	phosphorylation up-regulates →	EIF3F PThr119	phosphorylation down-regulates ⊣	EIF3F	19245811	SIGNOR-184185
CDK11B	phosphorylation up-regulates →	EIF3F PSer46	phosphorylation up-regulates →	EIF3F	19245811	SIGNOR-273133

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK11B	phosphorylation down-regulates	EIF3F	SIGNOR-95762
CyclinD3/CDK11B	phosphorylation → up-regulates activity	EIF3F	SIGNOR-273132
CyclinD3/CDK11B	phosphorylation → up-regulates activity	EIF3F	SIGNOR-273134
CDK11B	phosphorylation → up-regulates activity	EIF3F	SIGNOR-273131
CDK11B	phosphorylation → unknown	EIF3F	SIGNOR-184185
CDK11B	phosphorylation → up-regulates activity	EIF3F	SIGNOR-273133