| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN2 | WASL | Tyr256 | RETSKVIyDFIEKTG | dephosphorylation down-regulates | 16293614 | SIGNOR-141652 |
| ABL1 | WASL | Tyr256 | RETSKVIyDFIEKTG | phosphorylation up-regulates activity | 16199863 | SIGNOR-251437 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN2 | dephosphorylation down-regulates ⊣ | WASL PTyr256 | dephosphorylation up-regulates → | WASL | 16293614 | SIGNOR-141652 |
| ABL1 | phosphorylation up-regulates → | WASL PTyr256 | phosphorylation up-regulates → | WASL | 16199863 | SIGNOR-251437 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN2 | dephosphorylation![]() down-regulates | WASL | SIGNOR-141652 |
| ABL1 | phosphorylation → up-regulates activity | WASL | SIGNOR-251437 |