| Name | ACACB |
| ID | O00763 |
| Role | substrate |
| Enzymatic Domains |
Biotin carboxylation 259-761 PROSITE-ProRule
ATP-grasp 414-609 PROSITE-ProRule
Biotinyl-binding 888-962 PROSITE-ProRule
CoA carboxyltransferase N-terminal 1695-2025 PROSITE-ProRule
CoA carboxyltransferase C-terminal 2029-2345 PROSITE-ProRule |
View in  |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA2 | ACACB | Ser222 | PTMRPSMsGLHLVKR | phosphorylation down-regulates activity | 9148944 | SIGNOR-250318 |
| PRKAA2 | ACACB | Ser222 | PTMRPSMsGLHLVKR | phosphorylation down-regulates activity | 14613924 | SIGNOR-250316 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA2 | phosphorylation up-regulates → | ACACB PSer222 | phosphorylation down-regulates ⊣ | ACACB | 9148944 | SIGNOR-250318 |
| PRKAA2 | phosphorylation up-regulates → | ACACB PSer222 | phosphorylation down-regulates ⊣ | ACACB | 14613924 | SIGNOR-250316 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKAA2 | phosphorylation → down-regulates activity | ACACB | SIGNOR-250318 |
| PRKAA2 | phosphorylation → down-regulates activity | ACACB | SIGNOR-250316 |