Entity Details

Name CTDSP2
ID O14595
Role phosphatase
Enzymatic Domains
FCP1 homology 97-255
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CTDSP2SMAD3Ser204NHSMDAGsPNLSPNPdephosphorylation
up-regulates activity		17035229SIGNOR-248293
CTDSP2SMAD3Ser208DAGSPNLsPNPMSPAdephosphorylation
up-regulates activity		17035229SIGNOR-248294
CTDSP2SMAD3Ser213NLSPNPMsPAHNNLDdephosphorylation
up-regulates activity		17035229SIGNOR-248295
CTDSP2SMAD2Ser245NQSMDTGsPAELSPTdephosphorylation
down-regulates activity		17035229SIGNOR-248297
CTDSP2SMAD2Ser250TGSPAELsPTTLSPVdephosphorylation
down-regulates activity		17035229SIGNOR-248298
CTDSP2SMAD2Ser255ELSPTTLsPVNHSLDdephosphorylation
down-regulates activity		17035229SIGNOR-248299
CTDSP2SMAD2Thr220QSNYIPEtPPPGYISdephosphorylation
down-regulates activity		17035229SIGNOR-248296
CTDSP2SMAD1–dephosphorylation
down-regulates		16882717SIGNOR-148434
CTDSP2SMAD1Ser187NSHPFPHsPNSSYPNdephosphorylation
down-regulates activity		17085434SIGNOR-248300
CTDSP2SMAD1Ser195PNSSYPNsPGSSSSTdephosphorylation
down-regulates activity		17085434SIGNOR-248301
CTDSP2SMAD1Ser206SSSTYPHsPTSSDPGdephosphorylation
down-regulates activity		17085434SIGNOR-248302
CTDSP2SMAD1Ser214PTSSDPGsPFQMPADdephosphorylation
down-regulates activity		17085434SIGNOR-248303
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CTDSP2dephosphorylation
down-regulates
⊣
SMAD3
PSer204		dephosphorylation
down-regulates
⊣		SMAD317035229SIGNOR-248293
CTDSP2dephosphorylation
down-regulates
⊣
SMAD3
PSer208		dephosphorylation
down-regulates
⊣		SMAD317035229SIGNOR-248294
CTDSP2dephosphorylation
down-regulates
⊣
SMAD3
PSer213		dephosphorylation
down-regulates
⊣		SMAD317035229SIGNOR-248295
CTDSP2dephosphorylation
down-regulates
⊣
SMAD2
PSer245		dephosphorylation
up-regulates
→		SMAD217035229SIGNOR-248297
CTDSP2dephosphorylation
down-regulates
⊣
SMAD2
PSer250		dephosphorylation
up-regulates
→		SMAD217035229SIGNOR-248298
CTDSP2dephosphorylation
down-regulates
⊣
SMAD2
PSer255		dephosphorylation
up-regulates
→		SMAD217035229SIGNOR-248299
CTDSP2dephosphorylation
down-regulates
⊣
SMAD2
PThr220		dephosphorylation
up-regulates
→		SMAD217035229SIGNOR-248296
CTDSP2dephosphorylation
down-regulates
⊣
SMAD1
PSer187		dephosphorylation
up-regulates
→		SMAD117085434SIGNOR-248300
CTDSP2dephosphorylation
down-regulates
⊣
SMAD1
PSer195		dephosphorylation
up-regulates
→		SMAD117085434SIGNOR-248301
CTDSP2dephosphorylation
down-regulates
⊣
SMAD1
PSer206		dephosphorylation
up-regulates
→		SMAD117085434SIGNOR-248302
CTDSP2dephosphorylation
down-regulates
⊣
SMAD1
PSer214		dephosphorylation
up-regulates
→		SMAD117085434SIGNOR-248303
Regulator Mechanism/Effect Target SIGNOR-ID
CTDSP2dephosphorylation
→
up-regulates activity 		SMAD3SIGNOR-248293
CTDSP2dephosphorylation
→
up-regulates activity 		SMAD3SIGNOR-248294
CTDSP2dephosphorylation
→
up-regulates activity 		SMAD3SIGNOR-248295
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD2SIGNOR-248297
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD2SIGNOR-248298
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD2SIGNOR-248299
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD2SIGNOR-248296
CTDSP2dephosphorylation
img/direct_inhibition.png
down-regulates 		SMAD1SIGNOR-148434
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD1SIGNOR-248300
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD1SIGNOR-248301
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD1SIGNOR-248302
CTDSP2dephosphorylation
→
down-regulates activity 		SMAD1SIGNOR-248303