| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA3 | KCNK3 | Ser393 | GLMKRRSsV | phosphorylation up-regulates activity | 21357689 | SIGNOR-172470 |
| ROCK1 | KCNK3 | Ser393 | GLMKRRSsV | phosphorylation up-regulates activity | 21838752 | SIGNOR-176029 |
| PRKACA | KCNK3 | Ser393 | GLMKRRSsV | phosphorylation up-regulates activity | 21357689 | SIGNOR-172430 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA3 | phosphorylation up-regulates → | KCNK3 PSer393 | phosphorylation up-regulates → | KCNK3 | 21357689 | SIGNOR-172470 |
| ROCK1 | phosphorylation up-regulates → | KCNK3 PSer393 | phosphorylation up-regulates → | KCNK3 | 21838752 | SIGNOR-176029 |
| PRKACA | phosphorylation up-regulates → | KCNK3 PSer393 | phosphorylation up-regulates → | KCNK3 | 21357689 | SIGNOR-172430 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KA3 | phosphorylation → up-regulates activity | KCNK3 | SIGNOR-172470 |
| ROCK1 | phosphorylation → up-regulates activity | KCNK3 | SIGNOR-176029 |
| PRKACA | phosphorylation → up-regulates activity | KCNK3 | SIGNOR-172430 |